qnr prevalence in extended spectrum beta-lactamases (esbls) and none- esbls producing escherichia coli isolated from urinary tract infections in central of iran

Authors

iraj pakzad department microbiology, faculty of medicine and clinical microbiology research center, ilam university of medical sciences, ilam, iran

sohbhan ghafourian department microbiology, faculty of medicine and clinical microbiology research center, ilam university of medical sciences, ilam, iran

morovat taherikalani department microbiology, faculty of medicine and clinical microbiology research center, ilam university of medical sciences, ilam, iran

norkhoda sadeghifard department microbiology, faculty of medicine and clinical microbiology research center, ilam university of medical sciences, ilam, iran

abstract

objective(s) extensive use of quinolones has been associated with raising level of resistance. in the current, we focused on assessing the prevalence of escherichia coli resistance to quinolones and frequency of qnra, qnrb and qnrs in non esbls (extended spectrum beta-lactamases) and esbls producing e. coli with blashv and blatem. materials and methods one hundred and fifty e. coli isolates were identified during mar. 2007 to apr. 2008 in milad (tehran) hospital. they were tested for esbls production as well as quinolone resistance. pcr was performed for detection of blashv and blatem as well as qnra, b and s. results of 150 isolates, forty-two (28%) esbls producing and one hundred and eight (72%) non-esbls producing e. coli were identified. 64.2% (n= 24) of e. coli producing esbls and 4.62% (n= 5) of non-esbls e. coli were resistance to ciprofloxacin. 95.2% (n= 40) and 26.1% (n= 11) of the isolates harbored blatem and blashv, respectively. 23.8% (n= 10) had both genes. 37.5% (n= 9) and 20.8% (n= 4) of esbls producing e. coli were positive for qnra and qnrb respectively. qnrs was not identified in any isolate. conclusion our study showed high frequency of esbls producing e. coli as well as quinolone resistance genes (qnra, qnrb) in milad hospital.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

qnr Prevalence in Extended Spectrum Beta-lactamases (ESBLs) and None- ESBLs Producing Escherichia coli Isolated from Urinary Tract Infections in Central of Iran

Objective(s) Extensive use of quinolones has been associated with raising level of resistance. In the current, we focused on assessing the prevalence of Escherichia coli resistance to quinolones and frequency of qnrA, qnrB and qnrS in non ESBLs (extended spectrum beta-lactamases) and ESBLs producing E. coli with blaSHV and blaTEM. Materials and Methods One hundred and fifty E. coli isolates ...

full text

qnr Prevalence in Extended Spectrum Beta-lactamases (ESBLs) and None-ESBLs Producing Escherichia coli Isolated from Urinary Tract Infections in Central of Iran

OBJECTIVES Extensive use of quinolones has been associated with raising level of resistance. In the current, we focused on assessing the prevalence of Escherichia coli resistance to quinolones and frequency of qnrA, qnrB and qnrS in non ESBLs (extended spectrum beta-lactamases) and ESBLs producing E. coli with blaSHV and blaTEM. MATERIALS AND METHODS One hundred and fifty E. coli isolates wer...

full text

[Extended-spectrum beta-lactamases (ESBLs) producing bacteria].

TEM- or SHV-type extended-spectrum beta-lactamases(ESBLs) are of clinical concern in Europe and the United States, whereas bacterial strains producing such types of ESBLs had not been reported in Japan for many years. Toho-1, a different type class A ESBL, has been reported in 1995, in which any prototypical enzyme has not been identified so far. At present Toho-1 is the major ESBL in Japan, ho...

full text

The detection of Extended Spectrum Beta-Lactamases (ESBLs) producing Escherichia coli isolated from clinical samples

Urinary tract infections (UTIs) are a stern public health problem and are caused by a wide range of pathogens, but most frequently by Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis and Staphylococcus saprophyticus. High frequency rates and increasing antimicrobial resistance among uropathogens threaten to greatly raise the economic load of these infections. Fe...

full text

Prevalence and molecular characterization of Extended Spectrum Beta-Lactamases (ESBLs) producing Escherichia Coli and Klebsiella Pneumoniae.

UNLABELLED The aim of this study was to determine the prevalence of ESBL-producing Escherichia coli and Klebsiella pneumoniae as well as genes encoding ESBLs. MATERIAL AND METHODS A total of 1207 non-repeat isolates of E. coli and K. pneumoniae were obtained from urine, tracheal aspirate, wound swab and blood from patients hospitalized at the University Clinics in Skopje. ESBL set and E-test ...

full text

Prevalence of Extended-Spectrum Beta-Lactamases Enzymes in Enterobacter Aerogenes Isolated from Urinary Tract Infections in Shahrekord City

Introduction: Enterobacteriaceae produce the Extended-Spectrum Beta-Lactamases which is considered as an important resistant mechanism of beta-lactam antibiotics. The resistance to beta-lactam antibiotics is the main problem in the bacterial infections therapy. The prevalence of these enzymes changes in different geographical areas and with time. The present study aims to explore the frequency ...

full text

My Resources

Save resource for easier access later


Journal title:
iranian journal of basic medical sciences

جلد ۱۴، شماره ۵، صفحات ۴۵۸-۴۶۴

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023